Beilstein J. Org. Chem.2017,13, 2637–2658, doi:10.3762/bjoc.13.262
applications of those compounds will also be presented.
Keywords: dipeptide isosteres; monofluoroalkene-basedamidebonds; monofluoroalkenes; peptides; synthesis; Introduction
Nowadays, the pharmaceutical industry is interested in the development of new categories of drugs. While small molecules were the